Hawazen Fawzi Alwan Aljbour

Imbalance between Endogenous Antioxidants and Cellular Signaling Pathways in Immune-Mediated Diseases

There was growing evidence that many immune-mediated diseases were associated with chronic disturbances in cellular redox balance, which led to persistent inflammation. This paper reviewed the mechanisms linking reactive oxygen and nitrogen species (ROS/RNS), antioxidant defense systems, and redox-sensitive signaling p...