Rewiring the Glioma Ecosystem: Glial–Tumor Crosstalk, Immune Evasion, and Therapeutic Opportunities
This comprehensive review of the molecular mechanisms of glial–tumor crosstalk across all three major glial cells addresses glial–glial interactions as an independent regulatory layer and integrates recent spatial transcriptomic (ST) results revealing a structured, multi-glial niche that governs drug penetration.