Open access
Jul 2026
Upstream non-AUG initiation and ribosomal −1 frameshifting in ATXN8OS CTA/CTG repeat-associated translation
Abstract Microsatellite repeat expansions contribute to the pathogenesis of many neurodegenerative disorders. In spinocerebellar ataxia type 8 (SCA8), abnormal expansion of CTA/CTG repeats in the 3′ untranslated region of the ATXN8OS (ATXN8 Opposite Strand) gene has been implicated in disease pathology. Although the oc...
Soyoka Sakamoto, Hayato Ito, Mayuka Hasumi et al.
· Nucleic Acids Research · 0 citations