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He-Cheng Li

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Review Open access Sep 2026

The Adjuvant-Phase Dilemma After Neoadjuvant Chemoimmunotherapy in Resectable NSCLC: Evidence and Response-Guided Strategies

Simple Summary Perioperative immunotherapy, which includes treatment before and after surgery, has improved outcomes for some patients with resectable non-small cell lung cancer. However, current clinical trials usually test the entire treatment plan rather than the separate value of continuing immunotherapy after surg...

Jing-Yuan Fan, Yi-Chao Han, Run-Sen Jin et al. · 0 citations
Open access Aug 2026

PD09.07. Impact of Type 2 Diabetes on Outcomes of Neoadjuvant Therapy and Surgery for Esophageal Cancer: A Multi-Center Retrospective Study

Esophageal Cancer: Surgical Treatment of Esophageal Cancer – early outcomes and complications The prognostic impact of type 2 diabetes in esophageal cancer patients receiving neoadjuvant therapy followed by surgery remains unclear. We evaluated its association with perioperative outcomes and long-term surv...

Xi-Peng Wang, Zhi-Chao Liu, Xue-Feng Leng et al. · 0 citations
Review Sep 2026

Recent Advances and Future Challenges of Bispecific Antibodies in Lung Cancer.

Bispecific antibodies (BsAbs) integrate two binding specificities to coordinate antitumor mechanisms that cannot be readily achieved with conventional monospecific antibodies. In lung cancer, these agents encompass four principal strategies: dual targeting of tumor-associated receptors, immune-cell redirection, simulta...

Ming-Yuan Du, Yi-Chao Han, Run-Sen Jin et al. · 0 citations
Aug 2026

P1.086. Impact of Surgery Versus Non-Surgery on the Prognosis of Esophageal Cancer Patients With Clinically Identified Metastatic Supraclavicular Lymph Nodes

Esophageal Cancer: Adjuvant and Neo-Adjuvant Therapies The clinical significance of supraclavicular lymph node (SCLN) involvement in esophageal cancer remains controversial. The role of surgery in managing patients with SCLN metastases remains uncertain. This study evaluates the prognostic outcomes of pati...

Yiheng Huang, Yuqin Cao, He-Cheng Li · 0 citations
Open access Jul 2026

Targeting the FOXP3—T-bet interaction to restore Treg stability in IFN-γ—driven autoimmunity 2254306

Regulatory T cells (Tregs) maintain immune homeostasis through FOXP3-centered transcriptional complexes that tightly control lineage stability and suppressive function. However, how specific FOXP3 mutations disturb this complex and drive pathogenic Treg reprogramming in IPEX syndrome remains unclear. We identifie...

Bin Li, Wei-Qi Zhang, Xin-Nan Liu et al. · 0 citations

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