FAP-targeted gold nanocluster-mediated radioligand therapy in combination with TGF-βRI inhibition for tumor therapy.
Targeted radioligand therapy (TRT) is an emerging treatment modality that selectively delivers radioisotopes to tumors while sparing healthy tissues. However, optimizing TRT radiopharmaceuticals to concurrently achieve sustained tumor retention and rapid systemic clearance remains a fundamental challenge. Gold nanoclus...