Author

He-Jun Jiang

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Open access Sep 2026

USP18 Serves as a Key Mediator of cGAS‐STING for Cardiac Aging in Diabetes

ABSTRACT Diabetes accelerates cardiac aging, but the molecular mechanisms that link metabolic stress to myocardial senescence remain insufficiently defined. This study investigated factors driving diabetes‐associated cardiac aging with a focus on the role of USP18. Type 2 diabetes mellitus (T2DM) was induced in mice us...

Xun-Xi Deng, Z. Yin, Shi Tai et al. · Cell Biochemistry and Functi... · 0 citations

Review Jul 2026

AI-Driven Advances in Vascular Aging Research: From Mechanisms to Precision Medicine.

This review provides a comprehensive overview of current AI applications in vascular aging, spanning from basic mechanistic research to clinical risk prediction and discusses future directions and key challenges, including the need for external validation, algorithmic fairness, domain adaptation, and model interpretabi...

Zhongling Dai, Chenggong Ma, Yuke Chen et al. · Ageing Research Reviews · 0 citations