Review
Oct 2026
Genome-scale metabolic models enable predictive strain and process design for sustainable biomanufacturing.
Genome-scale metabolic models (GEMs) have emerged as powerful tools for optimizing microbial fermentation. This review traces the application of GEMs from model reconstruction through to industrial implementation. Automated reconstruction tools including CarveMe, ModelSEED, and RAVEN are discussed alongside quality-con...
Shuai-Shuai Xu, Ji Ding, Shu-Yi Chen et al.
· Biotechnology Advances · 0 citations