Quantitative FP-CIT PET analysis of dopaminergic degeneration in isolated REM sleep behavior disorder and early Parkinson's disease.
STUDY OBJECTIVES Isolated REM sleep behavior disorder (iRBD) is regarded as a prodromal stage of alpha-synucleinopathies such as Parkinson's disease (PD). This study aimed to identify dopaminergic alterations in patients with iRBD using 18F-FP-CIT PET. METHODS 18F-FP-CIT PET scans from 33 healthy controls (HC), 77 pa...