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Author

Heather C. Rice

2 papers indexed here

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Open access Oct 2026

Insulin regulates activity-dependent mitochondrial depolarization and calcium dynamics in dentate granule cells.

Systemic insulin resistance is associated with reduced hippocampal energy metabolism and cognitive impairment both in humans and animal models. However, whether insulin rapidly regulates neuronal metabolic stability during activity remains unclear. Here, we examined insulin signaling and queried the corresponding mitoc...

Beatriz Ferran, Hadyn Rose, J. Gray et al. · 0 citations
Open access Oct 2026

Female microglia show heightened responses to aging and amyloid pathology in mice and humans

INTRODUCTION Alzheimer’s disease (AD) displays pronounced sex differences, with women exhibiting greater prevalence and pathological burden than men. However, the molecular mechanisms underlying these differences remain elusive. Translation of preclinical findings to human AD remains challenging, potentially due to lim...

Jillian E. J. Cox, Ewa Poljańska, Sarah Ray et al. · 0 citations

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