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Heather N Currey

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Open access Aug 2026

Shared and distinct gain-of-function consequences from pathologic cytoplasmic versus nuclear TDP-43

New models with inactivating mutations in the nuclear localization sequence of TDP-43 are generated and phosphorylation-mediated neurotoxicity of both cytoplasmic and nuclear localized TDP-43 is controlled by the phosphatase calcineurin.

Aaron Long, Heather N Currey, Matvey Goldberg et al. · 0 citations

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