Sep 2026
HepG2 cells-derived exosomes exacerbate blue light-induced AMD-like retinal degeneration in A2E-laden ARPE-19 cells and BALB/c mice.
Exosomes derived from hepatic cells have emerged as important mediators of inter-organ communication and may contribute to retinal degeneration associated with age-related macular degeneration (AMD) through the liver-eye axis. However, their role in AMD pathogenesis remains poorly understood. In this study, we investig...
A. Seol, Jea Sic Jeong, Ji Eune Kim et al.
· Experimental Eye Research · 0 citations