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Sep 2026

Nitric oxide-entrapping bio-adhesive coacervate foam for multi-target therapy of gastrointestinal infections.

Bacterial biofilms and persistent inflammation undermine conventional antibiotic therapy for gastrointestinal infections, necessitating integrated therapeutic strategies. Here, we develop a nitric oxide (NO)-entrapping coacervate foam (LA-CHSF-NO) from α-lipoic acid-grafted chitosan and sodium alginate that synergistic...

Jie Wang, Shen-Yuan Ouyang, Zhou-Yang Tan et al. · 0 citations
Open access Aug 2026

Water-triggered in-situ gelling phospholipid oil enema for enhanced budesonide delivery and mucosal healing in ulcerative colitis

This water-triggered in situ gelling phospholipid oil platform addresses critical limitations of conventional BUD enemas by combining sustained local drug delivery with physical mucosal protection, offering a promising therapeutic strategy for comprehensive mucosal healing in UC.

Ting Ouyang, Yu-Mo Chen, Yi-Ying Jia et al. · 0 citations

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