Aug 2026
7,8-dihydroxyflavone exerts neuroprotective effects against traumatic brain injury in mice via the TrkB-dependent anti-ferroptotic ERK/CREB/GPX4 pathway.
7,8-DHF relieves TBI-induced neuronal damage, ferroptosis and neuroinflammation through the TrkB/ERK/CREB/GPX4 cascade, offering an alternative therapeutic strategy for TBI secondary injury.
Jian Song, Gu-Zheng Xu, Li Wang et al.
· Experimental Neurology · 0 citations