Lachnospiraceae and Its Metabolite Malate Act in Concert to Repair Gut Microbiota Imbalance and Block Colorectal Cancer Progression.
BACKGROUND Gut microbiota dysbiosis is a crucial driver of the initiation and progression of colorectal cancer (CRC), where functional gut microbes and their metabolites play key roles in the microecological regulation of CRC. Currently, the association between Lachnospiraceae and CRC progression, as well as the underl...