Author

Henrique Borges da Silva

2 papers indexed here

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Open access Jul 2026

Pannexin-1 promotes CD8+ T cell antitumor immunity against colorectal cancer in a gender-dependent way 2256739

Colorectal cancer (CRC) is the second leading cause of cancer death in the U.S., with stage IV patients showing poor five-year survival. Immune checkpoint blockade shows limited efficacy in CRC, highlighting the need to better understand how CD8+ T cells are regulated by the tumor microenvironment (TME). In the T...

Alma Banuelos, Henrique Borges da Silva, C. Loureiro · Journal of Immunology · 0 citations

Aug 2026

Astrocytic NFIX regulates thalamocortical circuits through GABA and purinergic signaling.

These studies identify region-specific roles for astrocytic NFIX and its gene regulatory network in TRN astrocytes, while further revealing that astrocytes in the TRN couple regulation of thalamocortical circuit dynamics and memory formation through parallel GABA and purinergic signaling pathways.

Sanjana Murali, Manuel Silva-Pérez, Junsung Woo et al. · Neuron · 0 citations