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Henry A. Holleb

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Open access Aug 2026

A Holistic View of Water Environments in Molecular Crystals

Hydrates are common solid forms that can significantly affect a compound’s stability, physicochemical properties, and commercial viability. Despite their importance in pharmaceutical development, hydrate structures, their relationship to material properties, and their propensity for formation remain poorly understood...

Henry A. Holleb, Fragkoulis Theodosiou, Pablo Martinez-Bulit et al. · Crystal Growth & Design · 0 citations