In Silico Study of Micheliolide Derivatives as Potential Non-Small Cell Lung Cancer Drugs Targeting the Epidermal Growth Factor Receptor.
OBJECTIVE To identify Micheliolide-based derivatives with favorable drug-like properties and inhibitory potential against the epidermal growth factor receptor (EGFR) using an integrated in silico approach. METHODS Micheliolide derivatives were evaluated for pharmacokinetic and toxicity profiles using SwissADME and AD...