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Author

Hernán Terenzi

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Open access Sep 2026

A proof-of-concept on transcription factor EL222 bioconjugation for targeted DNA cleavage.

The development of site-specific artificial nucleases remains a significant challenge in chemical biology. Here, we report the design and biophysical characterization of a light-responsive protein-small molecule hybrid based on the EL222 transcription factor. Through protein bioconjugation, we converted the native LOV-...

Matheus S. S. Paqui, D. Durigon, F. Xavier et al. · 0 citations

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