Open access
Sep 2026
Single-cell profiling and genetic regulation of alternative polyadenylation in the human brain.
Alternative polyadenylation (APA) has a central role in regulation of the fate of mRNA and exhibits high variability in the brain and in neurons. However, brain APA regulation has not been mapped at cell type resolution, and the genetic control of APA in brain cell types and its contribution to genetic disease have rem...
Jiu-Hong Nan, Carles A. Boix, Shao-Hui Shi et al.
· Nature Genetics · 0 citations