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Author

Hicham Drissi

3 papers indexed here

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Open access Sep 2026

Single‐cell transcriptomics reveals critical role of CD74 in bone marrow–derived mesenchymal stem cells

Abstract Background Human bone marrow aspirates have been widely used for skeletal tissue regeneration. However, clinical outcomes of the tissue repair after transplantation are variable. Methods In this study, we analyzed the molecular signatures and osteogenic differentiation potential of bone marrow-derived mesenchy...

Qin-Qin Xu, Carson Curtis, Jia-Hao Zhang et al. · 0 citations
Open access Aug 2026

In vivo screen for osteoclast derived osteogenic factors using non-resorptive osteoclasts in zebrafish bone.

Bone homeostasis requires the balanced action of bone forming osteoblasts and bone resorbing osteoclasts. This balance is maintained through local as well as systemic factors. Loss of osteoclast resorptive activity leads to development of osteopetrosis with increased bone volume but reduced skeletal integrity. Identifi...

J. Caetano-Lopes, Valentina Daponte, Katia Urso et al. · 0 citations
Open access Jul 2026

PHLPP1 Regulates Inflammatory Signaling in Degenerated Nucleus Pulposus Cells in Mice and Humans

The findings identify PHLPP1 as a critical regulator coupling inflammatory amplification to matrix remodeling in degenerating intervertebral discs and nominate PHLPP1 inhibition as a potential disease-modifying therapeutic strategy for intervertebral disc degeneration.

Biplab Chatterjee, Nazir M. Khan, Tushar Singh et al. · 0 citations

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