Author

Hicham Mansour

3 papers indexed here

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Review Open access Sep 2026

Refining Lung Cancer Care: The Emerging Role of Liquid Biopsy in Screening, Diagnosis, and Precision Oncology

Lung cancer (LC) remains the leading cause of cancer-related mortality worldwide, representing a major public health challenge. Although low-dose computed tomography is currently the standard screening method for high-risk individuals to reduce mortality, its clinical performance is limited by false-positive findings a...

Hicham Mansour, Omayma Mazouji, Ayman El Hammouti et al. · Cancers · 0 citations

Open access Sep 2026

A Pilot Head-to-Head Comparison of Two Bisulfite Conversion Kits for NGS-Based DNA Methylation Analysis of Liquid Biopsy Samples from Colorectal Cancer

Given the important role of early detection in improving cancer outcomes, epigenetic alterations, particularly DNA methylation, have emerged as powerful biomarkers for cancer screening and diagnosis. However, methylation profiling of cfDNA (circulating free DNA) presents particular technical challenges because cfDNA is...

Omayma Mazouji, A. Ouhajjou, R. Incitti et al. · Cancers · 0 citations

Review Open access Sep 2026

PARP inhibitors across different malignancies: clinical applications, resistance mechanisms, and strategies to enhance efficacy through combination therapies

Poly-ADP-ribose polymerase (PARP) inhibitors represent a novel class of anticancer agents that leverage the principle of synthetic lethality to induce tumor cell death by disrupting defective DNA repair pathways. PARP inhibitors have demonstrated strong preclinical activity in tumors with homologous recombination (HR)...

A. Ouhajjou, Omayma Mazouji, Chakib Nejjari et al. · Frontiers in Cell and Develo... · 0 citations