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Author

Hieu-Huy Nguyen-Tran

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Open access Aug 2026

Tumor-Induced PDPN+ Lymphatic-like Endothelial Cells Promote Clear-Cell Renal Cell Carcinoma Progression Through Reciprocal BMP10-CXCL13 Signaling

A dysplastic population of PDPN+ lymphatic-like endothelial cells in clear-cell renal cell carcinoma is identified and a tumor-specific BMP10-CXCL13 signaling axis that drives ccRCC progression is defined, uncovering a previously unrecognized therapeutic vulnerability in this disease.

Tuong-Vi Nguyen, Hieu-Huy Nguyen-Tran, Thi-Ngoc Nguyen et al. · 0 citations

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