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Hina Kiriyama

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Aug 2026

Staphylococcal Extracellular Complement-Binding Protein Induces IL-4 Production in Murine Basophils.

A novel function of Ecb is revealed, the activation of basophils to produce IL-4 in an IgE-independent manner, and a dual Ecb contribution to immune evasion-by interfering with complement activation and skewing Th2 immunity-and a role in the development of allergic inflammation-by inducing IL-4 production is suggested.

Haruka Sakakibara, Shion Kamada, Rikuto Iwata et al. · 0 citations