Live probiotic encapsulation: process engineering, wall materials, and the translation gap to human gastrointestinal survival.
Probiotic viability from manufacture to colonic delivery is compromised by thermal processing, oxidative storage conditions, and sequential gastrointestinal (GIT) stresses, with cumulative losses exceeding 8 log10 CFU in unprotected preparations. Encapsulation addresses this challenge by shielding cells within protecti...