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Hirkani Y. Pawar

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Open access Oct 2026

Development and Optimization of Repaglinide Amorphous Solid Dispersion Using Polymer Blends and Factorial Design for Enhanced Solubility and Dissolution

The present study focuses on the fabrication and evaluation of an amorphous solid dispersion (ASD) system of repaglinide, a BCS Class II antidiabetic drug with poor aqueous solubility. The aim was to enhance the dissolution behavior and potential bioavailability of repaglinide using a polymer-based ASD approach. A poly...

M. Kengar, Sajida D. Dhalait, Hirkani Y. Pawar et al. · 0 citations

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