Open access
Sep 2026
IFN-γ–dominant immune shift is associated with reduced protective ILC2 responses in chronic kidney disease
Chronic kidney disease (CKD) progression is driven by an imbalance between inflammatory injury and tissue repair; however, the immune mechanisms that disrupt reparative pathways remain incompletely understood. Group 2 innate lymphoid cells (ILC2s) play protective roles in epithelial integrity and antifibrotic responses...
Yoshihiro Kuno, Hiroki Ishikawa, Ryuichi Nagashima et al.
· Frontiers in Immunology · 0 citations