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Hong-Bing Shen

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Sep 2026

Long-term exposure to fine particulate matter constituents and lung cancer risk in Chinese never-smokers.

Although long-term exposure to fine particulate matter (PM2.5) has been linked to lung cancer incidence in never-smokers (LCINS), evidence for PM2.5 constituents remains limited. This study included 262,785 never-smokers from the China Kadoorie Biobank, among whom 2646 LCINS cases were identified. Annual average concen...

Zhi-Li Xia, Yu-Ting Han, Yuan-Lin Mou et al. · 0 citations
Sep 2026

Characterization of the genomic and transcriptomic landscape of invasive non-mucinous lung adenocarcinoma based on IASLC grading.

BACKGROUND The IASLC grading system has prognostic utility and potential therapeutic implications in invasive non-mucinous lung adenocarcinoma (LUAD), but the molecular basis underlying the grading spectrum remains unclear. METHODS We performed whole-genome sequencing in 138 Chinese patients with invasive non-mucinou...

Lu He, Xian-Feng Xu, Ling-Feng Bi et al. · 0 citations
Aug 2026

Actionable genotypes beyond the coding sequence and their association with lifespan in the UK Biobank.

The findings demonstrate that functionally verified promoter variants represent a previously unrecognised determinant of mortality risk, highlighting the potential value of looking beyond coding sequences in future studies and provide clues that functional promoter variants may merit consideration when expanding action...

Congcong Chen, Jiawen Zhu, Ziye Xu et al. · 0 citations

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