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Hong-Bo Yuan

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Review Open access Sep 2026

Reconstruction of the hematopoietic system using bone marrow, thymus, and spleen organoids: Construction strategies and research advances.

Hematopoietic development and systemic homeostasis depend critically on specific three-dimensional (3D) microenvironments within the bone marrow, thymus, and spleen. Traditional two-dimensional (2D) cultures and animal models frequently fail to recapitulate human physiology due to spatial limitations and interspecies g...

Hong-Bo Yuan, Lin Bai · 0 citations

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