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Author

Hong Cheng

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Aug 2026

A CHMP2B‐Targeting Photodynamic Degrader Synergizes With GSK‐3 Inhibition to Unleash Pyroptosis‐Driven Antitumor Immunity

Conventional cancer therapies rarely induce robust antitumor immunity, as they typically trigger non‐immunogenic cell death and fail to counteract intrinsic immune resistance mechanisms. In this work, we develop a charged multivesicular body protein 2B (CHMP2B)‐targeting photodynamic degrader (Chat‐PDD) that both act...

Ying Chen, Yi Cen, Xiao-Cheng Ou et al. · 0 citations

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