Pentraxin 3 (PTX3), the prototypical long pentraxin, is a locally inducible soluble pattern-recognition molecule that participates in complement regulation, efferocytosis, extracellular-matrix organization, vascular homeostasis, host defense, and tissue repair. These properties have made PTX3 an attractive candidate bi...
Hong-Hao Guo, Wen-Wei Liu, Wang Xiang et al.· Journal of Autoimmunity· 0 citations
Ageing remodels the neuroimmune, metabolic, and vascular environment in ways that accelerate neuronal vulnerability and constrain tissue repair. Mesenchymal stromal cells (MSCs) and MSC-derived extracellular vesicles (MSC-EVs) are therefore attractive candidates for neurodegenerative disorders because their effects ext...