Author

Hong-Jie Huang

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Open access Sep 2026

PLXDC2 siRNA‐Mediated Intervention Attenuates Microglial Senescence Through cGAS‐STING Signaling

ABSTRACT Parkinson's disease (PD) is driven by neurodegeneration, iron accumulation, and microglial senescence, yet effective therapy is hindered by the blood–brain barrier (BBB). By constructing the largest‐to‐date single‐cell atlas of the human substantia nigra, we identified a marked upregulation of PLXDC2 in PD mic...

He-Yue Lu, Zi-Tian Zheng, Fei-Ran Wang et al. · Advancement of science · 0 citations

Open access Sep 2026

Clinical Outcomes of Arthroscopic Annular Release Around the Greater Trochanter in Severe Gluteal Muscle Contracture Cases: A Technical Note and Case Series

Severe gluteal muscle contracture often requires surgical release, yet conventional open procedures are associated with extensive soft tissue trauma, significant postoperative pain, and prolonged rehabilitation. This study aimed to introduce an arthroscopic annular release technique for severe gluteal muscle contractur...

Zi-Ren Zhou, Ruo-Fan Li, Fei-Er Song et al. · Orthopaedic Surgery · 0 citations