Hong-Juan Wang

Gut microbiota remodeling contributes to nicotine-associated behavioral improvement and restoration of serotonin-related metabolism in CUMS mice

Major depressive disorder is a heterogeneous neuropsychiatric disorder in which serotonin-related pathways remain important pharmacological targets. Nicotine has been reported to exert antidepressant-like effects, yet whether the gut microbiota contributes to these effects remains unclear. Here, we found that susta...