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Author

Hongkui Deng

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Open access Sep 2026

Scalable generation of T lymphocytes from human pluripotent stem cells in suspended organoids.

Human pluripotent stem cells (hPSCs) are a promising cell source for producing T cells for regenerative medicine and immunotherapy. However, it is challenging to develop a scalable suspension culture system for generating functional T lymphocytes from hPSCs. Here, we developed a Matrigel-based artificial thymic organoi...

Qi Lei, Yu-Di Miao, Feng Zheng et al. · 0 citations
Review Open access Aug 2026

The evolution of iPSC-based cell therapy across autologous and allogeneic pathways.

This review traces key field milestones and analyzes prospects and hurdles for next-generation iPSC therapies as autologous and allogeneic iPSC therapies complement each other for distinct clinical demands.

Anmin Wang, Yunpei Zhang, Hong-Kui Deng et al. · 0 citations

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