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Author

Hong Li

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Review Open access Sep 2026

Secreted frizzled-related protein 2 as a context-dependent extracellular signaling hub in development, tissue remodeling, and disease

sFRP2, a member of the secreted frizzled-related protein family, is an extracellular protein characterized by a cysteine-rich domain and a netrin-like (NTR) domain. By modulating ligand availability, receptor selection, and microenvironmental signal integration, sFRP2 exerts highly context-dependent biological effects....

Xiao-Ping Luo, Mian Li, Yi Huang et al. · 0 citations
Review Open access Aug 2026

Therapeutic potential of traditional Chinese medicine for hyperuricemia: mechanistic insights and clinical prospects

This review critically synthesizes recent advances in TCM for HUA, focusing on how natural products modulate uric acid production, renal/intestinal excretion, inflammation, and gut microbiota via the gut–kidney axis, and proposes a four-tier hierarchical framework that bridges molecular precision with systemic effects.

Hong Li, Si-Qi You, Xiao-Ping Luo et al. · 0 citations

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