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Hong-Lin Li

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Review Open access Aug 2026

Mitochondrial dysfunction-driven ferroptosis in cerebral ischemia-reperfusion injury: Mechanisms and therapeutic strategies (Review)

A multidimensional pathological network composed of multiple mitochondrial abnormalities, including mitochondrial reactive oxygen species bursts, Ca2+ overload and disruption of the mitochondrial quality control system, synergistically amplifies lipid peroxidation and drives neuronal ferroptosis across the pathophysiological progression of CIRI.

Jian-Hui Li, An-Nan Liu, Wei Gao et al. · 0 citations
Review Aug 2026

Pyroptosis in Alzheimer's disease: Mechanisms and neuroinflammatory networks.

Overall, pyroptosis provides a novel framework for understanding the interplay between neuroinflammation and neurodegeneration in AD; however, its cell-type-specific roles, stage-dependent effects, and translational potential remain to be fully elucidated.

Xin-Kai Wu, Qiuyan Ye, Ming-Sheng Zi et al. · 0 citations

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