Tetrandrine attenuates hypoxia-induced microglial M1 polarization and microglia-mediated photoreceptor cell injury through modulation of NF-κB/p65 signaling.
Tet alleviates hypoxia-induced microglial M1 polarization and microglia-mediated photoreceptor cell injury, at least partly through modulation of NF-κB/p65 signaling, which identifies Tet as a candidate compound for further preclinical investigation in retinal neuroinflammation associated with DR.