Open access
Sep 2026
A Circulating Proteomic Signature of Allostatic Load Is Associated with Multisystem Disease and Mortality
Background: Chronic stress contributes to the development of cardiometabolic, malignant, and other chronic diseases through cumulative multisystem physiological dysregulation, conceptualized as allostatic load (AL). However, traditional AL relies on heterogeneous clinical biomarkers that are frequently unavailable or i...
Yu-Fan Guan, Jie Shen, Li Li et al.
· Proteomes · 0 citations