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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Hong-Miao Yao

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Oct 2026

Discovery of Novel Pyrazole-4-Carboxamide and Aromatic Carboxamide Derivatives Containing a Trans-2-(Trifluoromethyl)cyclopropyl Moiety as Potential SDHIs

A series of racemic pyrazole-4-carboxamide and aromatic carboxamide derivatives bearing a trans-2-(trifluoromethyl)cyclopropyl moiety were designed and synthesized as potential succinate dehydrogenase inhibitors (SDHIs). The compounds were evaluated for their in vitro and in vivo antifungal activities. Compound 10h s...

Jian Wang, Zi-Yue Zhang, Meng-Jie Tian et al. · 0 citations

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