Endowing Flexibility of Alveolar Type II Cells to Recapitulate Development From Lung Bud to Alveoli
ABSTRACT Alveolar type 2 (AT2) cells, which originate from bud tip progenitors during lung development, maintain pulmonary homeostasis through surfactant secretion and regenerative capacity, yet their plasticity has been challenging to model in vitro, limiting their applications in disease modeling and regenerative the...