Environmental-related concentrations of 6PPD-quinone drives intestinal toxicity via neutrophil extracellular traps: A novel mechanism of rubber-additive contamination.
The ubiquitous distribution of 6PPD-quinone (6PPD-Q), a transformation product of the widely used tire antioxidant 6PPD, across various environmental matrices has raised growing concern over its potential health risks. Nevertheless, the involvement of neutrophils in 6PPD-Q-induced biotoxicity remains poorly understood,...