Open access
Oct 2026
Structural network alterations and peripheral immune-inflammatory dysregulation define distinct subtypes of major depressive disorder with prognostic implications
Abstract Background Immune-inflammatory dysregulation and cortical structural vulnerability have been increasingly implicated in major depressive disorder (MDD). However, how they interact with each other, and whether immune heterogeneity in MDD is systematically organized by structural networks, remain unclear. Method...
W. Du, M. Yuan, Zi-Yang Gao et al.
· Psychological Medicine · 0 citations