Hong-Tao Bi

Lichen-Derived Polysaccharide from Cladina rangiferina Alleviates UVB-Induced Skin Photoaging: Potential Role of the NRF2-Mediated Antioxidant Response

In a previous study, we isolated a water-soluble heteropolysaccharide (CRWP-S) from the edible lichen Cladina rangiferina (L.) Nyl., which exhibited potent free radical-scavenging capacities. However, its protective efficacy against ultraviolet B (UVB)-induced skin photoaging and the underlying molecular mechanisms rem...

Advances in erythritol production through synthetic biology and systems metabolic engineering

Cellulosome engineering as biological macromolecular assembly for lignocellulose deconstruction: Structure, interactions, and functional design.

This review frames cellulosome engineering as a process-aware macromolecular assembly problem, in which catalytic balance, substrate targeting, assembly size, inter-domain spacing, and environmental robustness must be optimized together.