Background: Traditional bulk tissue analyses obscure the precise spatial compartmentalization of nicotine and its molecular effects within individual anatomical regions. This study aimed to develop and apply a high-resolution spatial multi-omics framework to characterize the localized disposition and functional respons...
It is indicated that the DR condition was associated with remodeling of LPS-challenged BV2 microglial-like states, attenuation of inflammatory programs, and increased neurotrophic outputs relative to LPS, without significantly reducing CCK-8-assessed metabolic activity.
Yi-Han Liu, Hao Yu, Jing-Bin Zhang et al.· Frontiers in Immunology· 0 citations
Multiomics analysis integrates complementary molecular layers to decode biological complexity; however, the secretome, representing the extracellular and dynamic response of cellular function, remains largely absent from existing multiomics frameworks. Secretome profiling has been constrained by high background inter...
Cai-Wei Hu, Jia-Liang Zhao, Qian Li et al.· Analytical Chemistry· 0 citations
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.