Advances and challenges in electrochemical detection of α-synuclein: Toward precision diagnosis of Parkinson's disease.
α-Synuclein (α-Syn) is a pivotal biomarker for Parkinson's disease (PD) and related synucleinopathies. However, the sensitive and selective detection of pathological α-Syn remains highly challenging because of its low abundance, structural heterogeneity, and diverse aggregation states. No single analytical platform cur...