Molecular evolutionary dynamics of Coxsackievirus A16 in Shenzhen, China, 2012-2022.
OBJECTIVES To investigate the epidemiological and genetic characteristics of Coxsackievirus A16 (CVA16) associated with hand, foot and mouth disease (HFMD) in Shenzhen, China. METHODS CVA16 was examined by a real-time RT-PCR method. Complete VP1 gene sequences of CVA16 strains were determined, and sequence analyses w...