Author

Hong-Yu Wang

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Open access Sep 2026

MAL2-Driven Lipid Droplets as Trojan Horses: Subverting Immune Surveillance to Promote Colorectal Cancer Liver Metastasis.

Colorectal cancer liver metastasis (CRLM) represents a formidable clinical challenge, yet the metabolic mechanisms by which tumor cells dismantle hepatic immune surveillance and remodel the tumor microenvironment (TME) remain elusive. Here, integrating single-cell RNA sequencing (scRNA-seq), transcriptomic analysis, an...

Shi-Peng Dai, Zi-Yuan Liu, Jun-Jie Sun et al. · Cancer Letters · 0 citations

Open access Aug 2026

Immunotherapy-based salvage therapy in advanced soft tissue sarcoma after first-line chemotherapy: a retrospective single-center analysis with emphasis on undifferentiated pleomorphic sarcoma

Introduction Soft tissue sarcomas (STS) are rare mesenchymal malignancies with limited treatment options in advanced stages. Anthracycline-based chemotherapy remains the standard of care but yields modest outcomes with significant toxicity, underscoring the need for more effective strategies. Methods We retrospectively...

Zhi-Chao Liao, Jun Huang, Hao-Tian Liu et al. · Frontiers in Immunology · 0 citations