Open access
Oct 2026
hsa_circ_0001377 promotes hepatic fibrosis by sponging let-7a-5p and targeting TGFBR1, Smad2, and Col1a2
Background: Hepatic fibrosis (HF) is primarily driven by the activation of hepatic stellate cells (HSCs) and is characterized by excessive extracellular matrix (ECM) accumulation. Circular RNAs (circRNAs) have recently gained increasing attention in HF research. Methods: RNA sequencing and bioinformatic analyses reveal...
Jia-Ming Zhou, Jia-Xuan Liu, Di Wu et al.
· Frontiers in Pharmacology · 0 citations