Hong-Yu Zhao

Macrophage lipid metabolism and inflammasome activation in rheumatoid arthritis: emerging mechanisms and therapeutic implications

Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by persistent synovial inflammation, synovial hyperplasia, cartilage destruction, and bone erosion. Within the multicellular RA synovial network, macrophages act as important inflammatory effectors and metabolic sensors whose functional states are...