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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Hong Zhao

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Open access Sep 2026

Peripheral Blood Transcriptomic Features Distinguishing Postpartum Depression from Major Depressive Disorder and Healthy Postpartum Controls

Purpose Postpartum depression (PPD) is a common mental disorder, yet its pathogenesis remains incompletely understood. This study compared peripheral blood mononuclear cell (PBMC) transcriptomes across three cohorts-PPD, major depressive disorder (MDD), and healthy postpartum control (HPC)-to elucidate the molecular me...

Lvping Lin, Han Tang, Hong-Jun Kuang et al. · 0 citations
Review Open access Aug 2026

Progress and challenges in exploring the pathogenesis of depressive disorders via RNA sequencing

Current evidence indicates that immune-inflammatory activation, impaired synaptic plasticity, and mitochondrial energy metabolism dysfunction constitute shared core pathological mechanisms across these disorders, validating classical pathogenic hypotheses at the molecular level.

Bo-Yu Zhang, Shi-Zhong Zheng, Li-Hua Guo et al. · 0 citations

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