Aug 2026
Development and validation of an HPLC-MS/MS method for the quantification of Aficamten in human plasma and urine and application to a clinical pharmacokinetic study.
An innovative, rapid, and highly sensitive HPLC-MS/MS approach for quantifying aficamten concentrations in human plasma and urine is established and critical validation parameters including matrix effects, extraction recovery, carryover, and stability were assessed.
Xiao-Fei Wu, Aijing Liu, Adrienne Griffith et al.
· Journal of chromatography. B... · 0 citations